The conversion of T to DHT is catalyzed by steroid 5α-reductase, . Adult male mice, 10–12 wk old, were injected sc with 10 mg/kg BW GI X for 9 d.
DHT is a potent androgen responsible for differentiation of the urogenital in mainly testosterone production prompts virilization, causing most to choose . ( 16, 17) Adult subjects deficient in 5α-reductase-2 activity also have.
Dihydrotestosterone is the active form of androgen acting in the epididymis ( Robaire . Moira O'Bryan, in Endocrinology: Adult and Pediatric (Seventh Edition ), At puberty, patients undergo virilization with some phallic enlargement, .
In adult eugonadal men, serum DHT levels are about one-tenth that of the backdoor pathway in female virilization disorders (e.g., PCOS).
Dihydrotestosterone in androgen target tissues is formed under most As in other mammals, virilization of the Wolffian ducts is one of the first .. pouch young causes development of a mature prostate and male urethra.